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Prescription Drug Addiction Treatment: Oxycodone, OxyContin and Addiction

Medically Reviewed by
Virmarie Diaz Fernandez, MD FAPA
February 28, 2025

Pain Medication and Addiction

Painkillers – such as oxycodone, Percocet, and morphine – interact with the brain’s reward system in ways that can lead to dependency. While highly effective in treating and relieving pain, these medications can also have side effects like relaxing the body, reducing anxiety or stress, and creating feelings of euphoria. Over time, the body can develop tolerance, necessitating higher or more frequent doses, or even switching to more powerful opioids.

Many personal, psychological, and genetic characteristics, as well as environmental aspects and circumstances, can contribute to developing an addiction. This makes it a complex and deeply personal struggle for many individuals.

A pile of prescription drug tablets

How Addictive is OxyContin?

OxyContin and oxycodone, commonly referred to as “oxy,” can be highly addictive if not consumed properly as indicated by a medical or healthcare professional. Oxycodone comes in other forms and brands, such as Roxicodone (also known as “roxies”). Opioids like these make up a large number of painkillers, and all opioids can lead to addiction. Similar to other painkillers, oxy works by binding to opioid receptors in the brain, resulting in reduced pain but also inducing a high sense of euphoria. With long-term use, the brain adapts, requiring higher dosages to achieve the same effect, leading to dependence and addiction.

Get help for oxy addiction now and verify your insurance with Eleanor Health today.

Prescription Drug Addiction Treatment and Recovery

Recovering from addiction requires a combination of medical and psychological support. In Eleanor Health clinics, as well as our online outpatient rehab program, addiction treatment commonly includes medication assisted treatment for safer detox and withdrawal; medication management to balance addiction medications with other prescriptions you have; different instances of individual and group therapies; and a support group or system, depending on your situation. 

Effective addiction treatment combines medical interventions, psychological therapy and strong support systems to help people regain control of their lives. By exploring your drug addiction treatment options, you can equip yourself with the necessary knowledge to confidently take the next step towards recovery and increase your chance of accomplishing long-term sobriety.

Addiction and Mental Health: Dual Diagnosis

Addiction is often fueled, in part, by mental and physical health challenges. Those struggling with addiction and depression, anxiety, and other mental health issues can worsen the risk of relapse and severity of withdrawal. In the case of painkiller prescription addictions, the experience of pain is another significant challenge to overcome. 

Some people may resort to opioid abuse as a desperate measure to deal with physical and or mental pain that feels unmanageable, growing dependent on opioids like OxyContin as a result. In the same way, prolonged use of pain-killing medicine can worsen preexisting mental health conditions that the person might suffer, creating a vicious cycle that is difficult to break without professional help.

Eleanor Health offers expert care for people facing co-occurring addiction with physical/mental health disorders. This is called a dual diagnosis and can be faced with the right treatment and therapy.

What is OxyContin?

OxyContin is a branded name medication containing the opioid oxycodone, often used as a pain reliever. OxyContin, with its extended release formula, was designed to provide long-lasting relief by blocking the pain signals sent by the central nervous system to the brain. As a secondary effect, this also relaxes the person and induces a euphoria-like state. When consumed over extended periods of time, this can alter the brain chemistry, making the user dependent on it to achieve that state of mind.

Doctors monitor for and manage the possibility of withdrawal, and taking OxyContin more frequently or in larger doses will both increase the risk of addiction and put your doctor at a disadvantage to prevent dependence and withdrawal issues. Understanding the risks and effects is essential for anyone prescribed this medication or struggling with opioid dependence.

What is the Difference Between OxyContin and Oxycodone?

OxyContin and oxycodone are both opioid-based painkillers, but the difference lies in their formulation and effect:

  • Oxycodone is an immediate-release opioid that provides pain relief for about 4 to 6 hours.
  • OxyContin is an extended-release version of oxycodone designed to provide pain relief effects over a 12-hour period.

Due to its release characteristics, OxyContin is often prescribed for patients suffering from chronic pain. This also makes it a target for substance abuse, as tampering with the tablets or pills can speed up the release process, delivering a high dose of oxycodone all at once.

OxyContin: Addiction and Risk Factors

Multiple elements contribute to the addictive nature of OxyContin and constitute the risk factors for this medication. Being aware of the dangers is key to preventing and addressing opioid dependence.

Oxy and Alcohol: A Dangerous Combination

Mixing oxy and alcohol can have life-threatening consequences as both work as central nervous system depressants. These types of substances slow down brain activity, relaxing the user’s body and vital functions. Abuse can increase the risk of suffering respiratory failure, falling into a coma or even overdosing.

Symptoms of Drug Addiction to Painkillers

Like any addiction or substance abuse case, there frequently are signs or tells that one could look out for when suspecting or dealing with it.

Some addiction to painkiller signs could include: 

  • Using painkillers outside of medical guidance
  • Hiding or lying about drug use
  • Experiencing financial or legal trouble due to drug use

When treating with common symptoms of painkiller addiction include:

  • Increased tolerance and dosage needed
  • Withdrawal symptoms when off of it
  • Compulsive drug-seeking behavior
  • Mood swings and personality changes

Virmarie Diaz Fernandez, MD FAPA

Dr. Diaz Fernandez holds Board Certification from the American Board of Psychiatry and Neurology and is recognized as a Fellow of the American Psychiatric Association. She began her medical education at the University of Puerto Rico Medical School, where she completed her medical training and the first year of her Psychiatry Residency. She relocated to Gainesville, Florida, to complete her Psychiatry Residency at the University of Central Florida, serving as Chief Resident during her final two years. Her dedication to continuous professional development is reflected in her additional certifications in WPATH, Nutritional Psychiatry, Mindfulness, and Women’s Mental Health. Her clinical expertise spans both inpatient and outpatient settings, with a focus on minority mental health populations, including the LGBTQ+ and Latinx communities. She also has significant experience in working with survivors of human trafficking and providing Medication-Assisted Treatment (MAT). In her administrative career, Dr. Diaz Fernandez has served in pivotal roles such as Medical Director and National Medical Director, where she has shaped policies and quality measures to enhance mental health service delivery. Her leadership extends to education and mentorship, where she supervises and collaborates with mid-level providers, developing curricula and resources to enhance their professional growth. Her professional interests include interventional psychiatry, addiction, and community mental health, where she leverages her extensive expertise to make a meaningful impact on her patients and the broader community.

Addiction & recovery Blog Mental Health

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